Emphysematous Cholecystitis - The Deadly Variant
Authors: Dr Nursyafiqah Mohd Noor , Dr Mohammad Fathullah Rossman
Abstract
Emphysematous cholecystitis (EC) is a rare but severe form of acute cholecystitis, distinguished by the presence of gas within the gallbladder wall, lumen, or surrounding tissues. It predominantly affects elderly, diabetic, and immunocompromised individuals and carries a significantly higher risk of complications and mortality compared to typical acute cholecystitis.
A case study shown a 70 years old lady with comorbid of hypertension and hyperlipidemia presented to emergency department with two days history of abdominal pain which more over the epigastric region radiated to the right side with concurrent episodes of vomiting. She was also complaining of having loose stool for the past two days . However , no fever was documented . Upon examining her, vital sign was stable ,however in the abdomen, there was tenderness over the right iliac fossa with positive Murphy sign.Bedside transabdominal ultrasound of the gallbladder revealed mixed hypoechogenicity over the liver segment II surrounding the gallbladder with sludge and stone seen within . The common bile duct was dilated.She was then proceed to CECT which revealed distended gallbladder with thickened gallbladder wall measuring 0.5 cm in thickness. Calculus seen within the gallbladder measuring 1.6cm x 1.7 cm with heterogeneous and enhancing pericholecystic fluid. Multiple areas of wall defect also detected .
These findings suggestive of perforation. Infective markers showed raised in inflammatory cells which indicate infection. She was then initially treated with antibiotics and subsequently proceed to open cholecystectomy to remove the gallbladder. Her condition improved tremendously after antibiotics and surgical intervention . She was then discharged well soon after.
Keywords: Emphysematous cholecystitis ,EC, high mortality ,gallbladder gangrene, gallbladder perforation
Pubmed Style
Dr Nursyafiqah Mohd Noor, Dr Mohammad Fathullah Rossman. Emphysematous Cholecystitis - The Deadly Variant. SJE Med. 2026; 31 (July 2026): -. doi:10.24911/SJEMed.12-2613
Publication History
Received: February 06, 2026
Accepted: April 13, 2026
Published: July 31, 2026
Authors
Dr Nursyafiqah Mohd Noor
Hospital Tanjong Karang
Dr Mohammad Fathullah Rossman
Hospital Tanjong Karang