Case Report
SJEMed. 2021; 2(1): 92-95
Successful treatment of refractory status epileptics with a single dose of IV ketamine in a Saudi child - a case report
Authors: Amal Yousif, Muhammad T. Alrifai, Khaled Almasoud.
View PDF HTML Fulltext DOI: 10.24911/SJEMed/72-1593584416Abstract
Background: Status epileptics are classically defined as seizures that are continuous for 30 minutes or longer or repetitive seizures between which the patient does not regain consciousness. This study reports a case of a boy with a 2-hour seizure. Case Presentation: We present the case of a 7-year-old boy, who is known to have tuberous sclerosis (TSC2 gene mutation). On the day of presentation, the seizure had started with aura (epigastric pain with weakness in the face), then started to seize in a form left focal jerky movement with generalization associated with rolling up of the eyes, and lasted for 5 minutes; it was aborted clinically by lorazepam 0.1 mg/kg IV. However, the electroencephalography (EEG) showed subclinical seizure. The patient received a loading dose of phenytoin, 20 mg/kg IV, with no changes in the EEG; then Keppra (three doses) with a total of 40 mg/kg IV was given, but subclinical seizure still persisted. The patient was given one dose of Ketamine IV of 1 mg/kg, which resulted in complete cessation of the seizure activity within 3 minutes after injection, which was confirmed by prolonged EEG monitoring. The total duration of the seizure was 2 hours. Conclusion: Ketamine can be considered as a third-line drug in refractory status epilepticus.
Keywords: Status epilepticus, refractory status epilepticus, seizure, ketamine
© Copyright: Author(s)
Authors
Amal Yousif
Pediatric Emergency Department, King Abdullah Specialized Children Hospital, King Abdulaziz Medical City, Riyadh, Saudi Arabia
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Muhammad T Alrifai
Neurology Division, Pediatric Department, King Abdullah Specialized Children Hospital, King Abdulaziz Medical City, Riyadh, Saudi Arabia
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Khaled Almasoud
Pediatric Emergency Department, King Abdullah Specialized Children Hospital, King Abdulaziz Medical City, Riyadh, Saudi Arabia
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Correspondence to:
. Khaled Almasoud, Pediatric Emergency Department, King Abdullah specialized Children Hospital, King Abdulaziz Medical City, Riyadh, Saudi Arabia.; dr_khaledvic@hotmail.com
Publication history
Received 06 Jul 2020
Accepted 12 Oct 2020
Published online 01 Nov 2020
Published in print 21 Jan 2021
How to cite this article
Pubmed Style
Yousif A, Alrifai MT, Almasoud K. Successful treatment of refractory status epileptics with a single dose of IV ketamine in a Saudi child - a case report. SJEMed. 2021; 2(1): 92-95. doi:10.24911/SJEMed/72-1593584416
Web Style
Yousif A, Alrifai MT, Almasoud K. Successful treatment of refractory status epileptics with a single dose of IV ketamine in a Saudi child - a case report. https://www.sjemed.com/?mno=3435 [Access: March 28, 2023]. doi:10.24911/SJEMed/72-1593584416
AMA (American Medical Association) Style
Yousif A, Alrifai MT, Almasoud K. Successful treatment of refractory status epileptics with a single dose of IV ketamine in a Saudi child - a case report. SJEMed. 2021; 2(1): 92-95. doi:10.24911/SJEMed/72-1593584416
Vancouver/ICMJE Style
Yousif A, Alrifai MT, Almasoud K. Successful treatment of refractory status epileptics with a single dose of IV ketamine in a Saudi child - a case report. SJEMed. (2021), [cited March 28, 2023]; 2(1): 92-95. doi:10.24911/SJEMed/72-1593584416
Harvard Style
Yousif, A., Alrifai, . M. T. & Almasoud, . K. (2021) Successful treatment of refractory status epileptics with a single dose of IV ketamine in a Saudi child - a case report. SJEMed, 2 (1), 92-95. doi:10.24911/SJEMed/72-1593584416
Turabian Style
Yousif, Amal, Muhammad T. Alrifai, and Khaled Almasoud. 2021. Successful treatment of refractory status epileptics with a single dose of IV ketamine in a Saudi child - a case report. Saudi Journal of Emergency Medicine, 2 (1), 92-95. doi:10.24911/SJEMed/72-1593584416
Chicago Style
Yousif, Amal, Muhammad T. Alrifai, and Khaled Almasoud. "Successful treatment of refractory status epileptics with a single dose of IV ketamine in a Saudi child - a case report." Saudi Journal of Emergency Medicine 2 (2021), 92-95. doi:10.24911/SJEMed/72-1593584416
MLA (The Modern Language Association) Style
Yousif, Amal, Muhammad T. Alrifai, and Khaled Almasoud. "Successful treatment of refractory status epileptics with a single dose of IV ketamine in a Saudi child - a case report." Saudi Journal of Emergency Medicine 2.1 (2021), 92-95. Print. doi:10.24911/SJEMed/72-1593584416
APA (American Psychological Association) Style
Yousif, A., Alrifai, . M. T. & Almasoud, . K. (2021) Successful treatment of refractory status epileptics with a single dose of IV ketamine in a Saudi child - a case report. Saudi Journal of Emergency Medicine, 2 (1), 92-95. doi:10.24911/SJEMed/72-1593584416
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