Saudi Journal of Emergency Medicine

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Case Report
SJEMed. 2021; 2(1): 92-95

Successful treatment of refractory status epileptics with a single dose of IV ketamine in a Saudi child - a case report

Authors: Amal Yousif, Muhammad T. Alrifai, Khaled Almasoud.

View PDF HTML Fulltext DOI: 10.24911/SJEMed/72-1593584416

Abstract

Background: Status epileptics are classically defined as seizures that are continuous for 30 minutes or longer or repetitive seizures between which the patient does not regain consciousness. This study reports a case of a boy with a 2-hour seizure. Case Presentation: We present the case of a 7-year-old boy, who is known to have tuberous sclerosis (TSC2 gene mutation). On the day of presentation, the seizure had started with aura (epigastric pain with weakness in the face), then started to seize in a form left focal jerky movement with generalization associated with rolling up of the eyes, and lasted for 5 minutes; it was aborted clinically by lorazepam 0.1 mg/kg IV. However, the electroencephalography (EEG) showed subclinical seizure. The patient received a loading dose of phenytoin, 20 mg/kg IV, with no changes in the EEG; then Keppra (three doses) with a total of 40 mg/kg IV was given, but subclinical seizure still persisted. The patient was given one dose of Ketamine IV of 1 mg/kg, which resulted in complete cessation of the seizure activity within 3 minutes after injection, which was confirmed by prolonged EEG monitoring. The total duration of the seizure was 2 hours. Conclusion: Ketamine can be considered as a third-line drug in refractory status epilepticus.

Keywords:   Status epilepticus, refractory status epilepticus, seizure, ketamine


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Successful treatment of refractory status epileptics with a single dose of IV ketamine in a Saudi child - a case report


Authors
Amal Yousif
Pediatric Emergency Department, King Abdullah Specialized Children Hospital, King Abdulaziz Medical City, Riyadh, Saudi Arabia
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Muhammad T Alrifai
Neurology Division, Pediatric Department, King Abdullah Specialized Children Hospital, King Abdulaziz Medical City, Riyadh, Saudi Arabia
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Khaled Almasoud
Pediatric Emergency Department, King Abdullah Specialized Children Hospital, King Abdulaziz Medical City, Riyadh, Saudi Arabia
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Correspondence to:
. Khaled Almasoud, Pediatric Emergency Department, King Abdullah specialized Children Hospital, King Abdulaziz Medical City, Riyadh, Saudi Arabia.; dr_khaledvic@hotmail.com

Publication history
Received 06 Jul 2020
Accepted 12 Oct 2020
Published online 01 Nov 2020
Published in print 21 Jan 2021

How to cite this article

Pubmed Style

Yousif A, Alrifai MT, Almasoud K. Successful treatment of refractory status epileptics with a single dose of IV ketamine in a Saudi child - a case report. SJEMed. 2021; 2(1): 92-95. doi:10.24911/SJEMed/72-1593584416


Web Style

Yousif A, Alrifai MT, Almasoud K. Successful treatment of refractory status epileptics with a single dose of IV ketamine in a Saudi child - a case report. https://www.sjemed.com/?mno=3435 [Access: March 28, 2023]. doi:10.24911/SJEMed/72-1593584416


AMA (American Medical Association) Style

Yousif A, Alrifai MT, Almasoud K. Successful treatment of refractory status epileptics with a single dose of IV ketamine in a Saudi child - a case report. SJEMed. 2021; 2(1): 92-95. doi:10.24911/SJEMed/72-1593584416


Vancouver/ICMJE Style

Yousif A, Alrifai MT, Almasoud K. Successful treatment of refractory status epileptics with a single dose of IV ketamine in a Saudi child - a case report. SJEMed. (2021), [cited March 28, 2023]; 2(1): 92-95. doi:10.24911/SJEMed/72-1593584416


Harvard Style

Yousif, A., Alrifai, . M. T. & Almasoud, . K. (2021) Successful treatment of refractory status epileptics with a single dose of IV ketamine in a Saudi child - a case report. SJEMed, 2 (1), 92-95. doi:10.24911/SJEMed/72-1593584416


Turabian Style

Yousif, Amal, Muhammad T. Alrifai, and Khaled Almasoud. 2021. Successful treatment of refractory status epileptics with a single dose of IV ketamine in a Saudi child - a case report. Saudi Journal of Emergency Medicine, 2 (1), 92-95. doi:10.24911/SJEMed/72-1593584416


Chicago Style

Yousif, Amal, Muhammad T. Alrifai, and Khaled Almasoud. "Successful treatment of refractory status epileptics with a single dose of IV ketamine in a Saudi child - a case report." Saudi Journal of Emergency Medicine 2 (2021), 92-95. doi:10.24911/SJEMed/72-1593584416


MLA (The Modern Language Association) Style

Yousif, Amal, Muhammad T. Alrifai, and Khaled Almasoud. "Successful treatment of refractory status epileptics with a single dose of IV ketamine in a Saudi child - a case report." Saudi Journal of Emergency Medicine 2.1 (2021), 92-95. Print. doi:10.24911/SJEMed/72-1593584416


APA (American Psychological Association) Style

Yousif, A., Alrifai, . M. T. & Almasoud, . K. (2021) Successful treatment of refractory status epileptics with a single dose of IV ketamine in a Saudi child - a case report. Saudi Journal of Emergency Medicine, 2 (1), 92-95. doi:10.24911/SJEMed/72-1593584416


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