Hunan hand syndrome: benign capsaicininduced contact dermatitis presenting with alarming symptoms
Sarah Sultan
,
Sarah Mohammed Bin Hariz
,
Yassin Mohammed Saeed Hamad
,
Ayesha Almemari
Year:
2026
Background: Hunan hand syndrome (HHS) is a painful, self-limited capsaicin-induced contact dermatitis that occurs after exposure to Capsicum species. Capsaicin activates transient receptor potential vanilloid-1 receptors on nociceptive fibers, producing intense burning pain that can mimic the sensation of burns or allergic reactions. Although benign, HHS can prompt emergency department...
Continue Reading