Point-of-Care Ultrasound (POCUS) has emerged as a transformative diagnostic tool in cardiac arrest management, particularly for non-trauma cases, offering clinicians real-time, dynamic imaging to guide resuscitation efforts. As with any relatively new area of study, previous research on POCUS is limited and there is a lot of heterogeneity in studies’ methods, outcomes, and practiced contexts. This systematic review and meta-analysis aims to evaluate the effectiveness of point-of-care ultrasound (POCUS) in both identifying the cause of non-traumatic cardiac arrest and improving patient outcomes during treatment. A comprehensive search of multiple databases from January 2010 to December 2023 identified studies meeting rigorous inclusion criteria, focusing on adult patients and assessing outcomes such as Return of Spontaneous Circulation (ROSC), survival rates, and diagnostic accuracy. To support the high quality of the analysis, QUADAS-2 tool and the Cochrane risk of bias tool were employed. Pooled analysis was undertaken using RevMan with relative risks and 95% CIs for mortality, and I² test was used for measuring heterogeneity while clinical setting formed basis of the subgroup analysis. The research presented suggests that point-of-care ultrasound (POCUS) can help identify treatable causes of cardiac arrest, such as tamponade, pulmonary embolism, and hypovolemic shock, which can positively impact the chances of successful resuscitation and guide treatment during CPR. Nevertheless, unlike routine diagnostics, POCUS has high diagnostic precision and therapeutic application but still has several drawbacks: operator-dependency and unpredictable protocols. This review further emphasizes the relevance of POCUS in enhancing outcome of cardiac arrest about which prescribes a need for more national protocols with a view of enhancing its implementation.

Keywords: "Point-of-Care Ultrasound" OR "POCUS", combined with "Cardiac Arrest" AND "Non-Trauma"