Objective: This study aimed to evaluate job satisfaction and professional well-being among emergency staff (ED) staff in Madinah, Saudi Arabia. Methods: A descriptive, cross-sectional study was conducted among 295 ED staff (147 nurses and 148 physicians) at King Fahad Hospital and Alula Hospital. Participants were surveyed using a demographics data form and a validated 40-item Job Satisfaction Questionnaire measuring satisfaction across six dimensions. Results: ED staff reported high satisfaction with patient care and peer interactions, with 78% satisfied with patient quality and 85% with collegial support. However, dissatisfaction was significant for workload (62%), staffing (54%), supervisory support (60%), and training (68%). Job satisfaction positively correlated with age; 72% of staff aged 40 years and above reported satisfaction as compared to 55% of younger staff (p-value<0.01). Staff with over 10 years of experience had a satisfaction rate of 75%, while those with less than 5 years reported 50% (p-value<0.05). Non-Saudi nationals exhibited higher satisfaction (70%) compared to Saudi staff (55%), with no significant differences based on gender, marital status, or job type (p-value>0.05). Conclusion: Improving job satisfaction among ED staff requires a multifaceted approach, focusing on workload management, professional development, and enhancing the work environment. These efforts are essential for reducing stress levels and improving patient care quality.

Keywords: Job satisfaction, Emergency department, Healthcare professionals, Workload, Patient care, Training opportunities