Food protein-induced enterocolitis syndrome in an infant presenting with methemoglobinemia: A case report
Authors:
Abdulaziz Khaled Alareefy,
Hessah Hushan,
Adel Alsaedi
Background: Methemoglobinemia is a condition in which the iron in hemoglobin is oxidized from the ferrous to ferric state, resulting in oxygen desaturation and cyanosis. It can be congenital or acquired, with acquired causes including the ingestion of certain medications or chemical products or infections such as sepsis or gastroenteritis. Case presentation: Herein, we report the case of a young infant who presented with diarrhea and cyanosis and was found to have significant methemoglobinemia which most likely was secondary to severe diarrhea. It was managed successfully with methylene blue, he was diagnosed later as case of food protein induced enterocolitis syndrome. Conclusion: Clinicians should consider profound diarrhea as a potential cause of methemoglobinemia to enhance early intervention.
Keywords: Methemoglobinemia, Cyanosis, Diarrhea, Enterocolitis.
Authors
Correspondence to:
Abdulaziz Khaled Alareefy, Pediatric Emergency Department, King Fahad Medical City, Central Second Health Cluster, Ministry of Health, PO Box 59046, Riyadh, 11525, Saudi Arabia AbdulazizAr22@gmail.com
Publication history:
Received 10 Jun 2024
Revised 23 Jun 2024
Accepted 06 Jul 2024
Published online 25 Sep 2024
Alareefy AK, Hushan H, Alsaedi A. Food protein-induced enterocolitis syndrome in an infant presenting with methemoglobinemia: A case report. SJEMed. Online First: 25 Sep, 2024. doi:
10.24911/SJEMed.72-1717870966
Alareefy AK, Hushan H, Alsaedi A. Food protein-induced enterocolitis syndrome in an infant presenting with methemoglobinemia: A case report. https://sjemed.com/?mno=204919 [Access: January 22, 2025]. doi:
10.24911/SJEMed.72-1717870966
Alareefy AK, Hushan H, Alsaedi A. Food protein-induced enterocolitis syndrome in an infant presenting with methemoglobinemia: A case report. SJEMed. Online First: 25 Sep, 2024. doi:
10.24911/SJEMed.72-1717870966
Alareefy AK, Hushan H, Alsaedi A. Food protein-induced enterocolitis syndrome in an infant presenting with methemoglobinemia: A case report. SJEMed, [cited January 22, 2025]; Online First: 25 Sep, 2024. doi:
10.24911/SJEMed.72-1717870966
Alareefy, A. K., Hushan, . H. & Alsaedi, . A. (2025) Food protein-induced enterocolitis syndrome in an infant presenting with methemoglobinemia: A case report. SJEMed, Online First: 25 Sep, 2024. doi:
10.24911/SJEMed.72-1717870966
Alareefy, Abdulaziz Khaled, Hessah Hushan, and Adel Alsaedi. 2025. Food protein-induced enterocolitis syndrome in an infant presenting with methemoglobinemia: A case report. Saudi Journal of Emergency Medicine, Online First: 25 Sep, 2024. doi:
10.24911/SJEMed.72-1717870966
Alareefy, Abdulaziz Khaled, Hessah Hushan, and Adel Alsaedi. "Food protein-induced enterocolitis syndrome in an infant presenting with methemoglobinemia: A case report." Saudi Journal of Emergency Medicine Online First: 25 Sep, 2024. doi:
10.24911/SJEMed.72-1717870966
Alareefy, Abdulaziz Khaled, Hessah Hushan, and Adel Alsaedi. "Food protein-induced enterocolitis syndrome in an infant presenting with methemoglobinemia: A case report." Saudi Journal of Emergency Medicine Online First: 25 Sep, 2024. Web. 22 Jan 2025 doi:
10.24911/SJEMed.72-1717870966
Alareefy, A. K., Hushan, . H. & Alsaedi, . A. (2025) Food protein-induced enterocolitis syndrome in an infant presenting with methemoglobinemia: A case report. Saudi Journal of Emergency Medicine, Online First: 25 Sep, 2024. doi:
10.24911/SJEMed.72-1717870966